Mean Girls Cast 2024 Regina Mom. Busy has been cast as regina george’s mom, who was famously played by amy poehler in the original 2004 movie. Mean girls is a reimagining of the 2004 classic comedy film as a musical, directed by samantha jayne and arturo perez jr.

Here’s how the cast compares to the original movie that starred rachel mcadams and lindsay lohan. Tim will also be reprising his original movie role of principal duvall.